Question
Posted on: March 6 2013Betamethasone dipropionate 0.05%, salicylic acid 5%, isopropanol 35 ml, Klucel GF 500 mg and water up to 50 ml. In This lotion an unresolved part is left behind. How to avoid?
Answer
This composition is similar to the composition published in the TMF. However, there is 2% salicylic acid more. Presumably, it does not fully dissolve. The concentration of isopropanol could still be increased, but we are already reaching 70%; Another possibility exists in the addition of a certain amount of propylene glycol, but this is also not ideal. My proposal is to ask the prescribing physician to reduce the concentration of salicylic acid by 2%.