Question
Posted on: March 6 2013Counterfeiting Solution for Dentist
The composition was the following: Dexamethasone 0125 G; Phenol 36,705 g; Formaldehyde 32,410 G; Guaiacol 29,460 G; Excipient AD 100 g
The solution was packaged in vials of 13ml (sterile). How can this be best prepared. The dentist himself claims that the product did not give 2 phases or precipitation but that it was a nicely homogeneous solution.
Answer
Next composition could be found back
Acétate de déxaméthasone 0138 g Phénol 45,285 g Gaïacol 6,790 g Glycérol 22,770 g Eau purifiée 22,617 g Acétate D'amyle 2,400 g
On this basis, the following products are mixed together according to Apoth S. Crepel a homogeneous liquid:
dexamethasone Acetate 138 mg Phenol 36,705 g Guaiacol 29.460 g (These products in the same quantity as in the original preparation) Amylacetate 3.234 g Water and glycerol each 15,238 g
For the time being, the formol is omitted, because I also do not know well what concentration of formol solution can and should be used.
SUPPLEMENT
In Dental Practice, Mestal is using a 5% formaldehyde solution, which is prepared by dilution of the concentrated (35%) Formol solution. The sterility of this solution will not give a major problem due to the presence of a large amount of phenol, possibly formol. But the use of pre-autoclaved and drugged vials remains recommendable!