Question
Posted on: March 6 2013A dermatologist asks me to prepare the following: Tretinoine 0.1% as mouthwash.
Answer
This seems to me to be no easy task. I found the following formula and maybe it is also applicable at 0.1%:
constituents of I mix and heat up at 40 to 50 ° C to clear this warm solution slowly under good mixing casting in bulk of II dilute to 100 ml.
I tretinoin 0.05%Preparation
Crempohor EL 14g
propylene glycol 15g
Butylhydroxytolua 0.05 g
II Aqua conserv. AD 100ml
constituents of I mix and heat up at 40 to 50 ° C to clear this warm solution slowly under good mixing casting in bulk of II dilute to 100 ml.
Comment
I can not pronounce on the taste Because I suspect that this formula was not worked out to use as mouthwash. However, it has been specified that stored outside all the influence of the light at KT after 12 months still 95% of the content was recovered.