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Question

Posted on: March 6 2013

How do I make this preparation? Oestradiolbenzoaat 0.03 g Prednisolone 1 g Glycerol 10 g Capsicine TT 15 g Jaborandi TT 20 g camphor spiritus 120 g Aqua AD 300 ml

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Answer

I suppose that when the tincture mixture is diluted with water, an important precipitation arises? There is also the possibility that camphor is precipitable. Given the high concentration of alcohol, we need to choose a viscosities enhancement substance, which is compatible with this solvent. Therefore I would bring in a mortar 3 G hydroxypropylcellulose (Klucel GF), which I moisten with glycerin and there the tinctures mixture gradually add under good mixing the stamper. In a separate beaker, estradiol and prednisolone are dissolved in camphor spiritus and then this solution is mixed with the contents of the mortar. Afterwards, it is diluted with water under very good stirring with the pestle.