Question
Posted on: March 6 2013How to prepare capsules with duloxetine 30mg?
I would crush the granules, which are in Cymbalta capsules, and then envelop the capsules enteric. But I am told that you should not crush these granules. Is this correct? Should I mix them with lactose and try to divide them evenly into capsules. And if I do not crush the granules, do they have to be provided with an enteric envelope?
Answer
Hard gelatin capsules evenly filling with granules is a very difficult one not to say an impossible operation. Therefore, you will have to crush the granules into a fine powder and then provide the gelules with a gastro-resistant casing.