Question
Posted on: March 6 2013I need to make suppositories with the following compound: Folcodine 8mg papaverine 20mg eucalyptol 80mg camphor 80mg FSA suppo Child (2g) DT 10
Eucalyptol and camphor provide a melting point reduction of 2.4 ° C. Therefore, a base must be chosen with a melting tip of 38.4 ° C. This is possible with various white-soldered masses & #039; s but most of those masses & #039; s are no longer available. I thought to use the ordinary Suppobasis (Suppocire AS2X) with the addition of Aerosil to absorb the essential oil, but how much aerosil should be added? Are there any tables on this, or how should this be calculated? Do you have any other suggestions?
Answer
Let me start by saying that the piste with Aerosil will not bring much earth to the dike given the melting point reduction will occur nonetheless. Such a strong adsorption will not occur! You have correctly calculated the melting point cut, and you can now apply it in the chart, which can be found in & #039; > question 6 . I have taken it up again because all these white-soldered & #039; s are no longer available. So We are not going forward! The solutions of the problem with white protein mass & #039; s are clearly preferable because you may remember, wax has a high melting point and overheating of the suppository mass is not a good thing.