Question
Posted on: March 6 2013Ovulen with Econazole and amphotericin. Econazole 150mg amphotericin B 20mg FAC 16 pessaries
- How to make these pessaries? What form (number g), Suppomassa...
- after telephone contact with Bristol (Fungi zone = amphotericine + excipients) We recommend that you do not open and process the bottle!!! Amphotericine is not in bulk to get.
- Is There also no interaction between the 2 components of the preparation possible? The Martindale also explicitly highlights many interactions with Amphotericine....
- can this prescription be carried out?
Answer
Working with amphotericin B is not without risk. One finds the following warning: "Potential Acute Health Effects: Hazardous in case of skin contact (irritating), or inhalation". Therefore, it should be recommended to avoid strong dust formation and wear both gloves and a mouth mask. Ideal to be able to work in an exhaust cabinet. I do not suspect an interaction between the two components and the interactions you have found have been seen as interactions with various medicines, which are quite numerous. Here a local action is envisaged for a persistent fungal infection. These ovulen can be made in the classic way with ADEPs solidus, 4g pessaries.