Question
Posted on: March 6 2013This preparation appears to strike down: saponin coaltar 8g Salicylic acid 8g Resorcine 3g Propylene glycol 25g Methylprednisolone 320mg dexamethasone 80mg Isopropanol 80ml
AQUA 100ml < br/> I dissolve salicylic acid in isopropanol, then add water in which Sulpho resorcinol is already dissolved but then the problem arises when adding saponin Coaltar: A large amount of flushy precipitation arises.
Answer
Methylprednsisolon and dexamethasone can be dissolved in propylene glycol but by diluting with water they will also precipitate in addition to components from LCD. An increase in the amount of isopropanol in subtracting from the amount of water e.g. to 130ml and water 50ml can provide a solution. In addition comes the possibility of the preparation of a suspension. To avoid any problem, use best hydroxyprpylcellulose as a viscosities enhancement substance in a concentration of 1 à 2%..