To recipes helpdesk

Question

Posted on: March 6 2013

A shampoo with problems: Lactic acid 3g Salicylic Acid 6g Miglyol 812 2% Nalsulfate 60g nystatin 2 milj E erythromycin 2g Aqua AD 300cc

  • What is the function of Miglyol? Can it be used to solubilize salicylic acid? Do we not need to use Cetomacrogol anymore?
  • Nystatin also best solubilize concurrently with salicylic acid?

Answer

Your prescription is very similar to question: ' Do you have a proposal concerning the implementation of next shampoo? ' The amount of Miglyol is insufficient to dissolve 6g of salicylic acid. I suspect it is added to dry the hair not too brightly. Salicylic acid can possibly be solubilised by adding 24g of Cetomacrogol, which should also dissolve the Miglyol. To bring erythromycin into solution a too large amount of alcohol will need to be added. So best suspending along with Nystatin. So I would start to melt Cetomacrogol and add to the melting salicylic acid and Miglyol. Then slowly add 50ml of water and check if everything remains solved. Afterwards can be further diluted with a second quantity of 50ml of water. Everything needs to be solved?? NaLS are dissolved in 150ml of water to which lactic acid was added. This solution is slowly added to the previous under hard stirring. Everything should remain resolved. The erythromycin and the Nystatin are mixed in a mortar and rubbed with a small part of that solution and the suspension is further diluted with the remaining part. Eventually it is brought to volume. If the undissolved products are too fast after shaking, a slight viscosity increase can be carried out using methyl cellulose.