Question
Posted on: March 6 2013We get occasional prescriptions of fluphenamine acid gel 5%.
We try to deal with the same formula as the 3% fluphenamine acid gel (Klucel). While adding the Hydroxypropyl cellulosic gel, the preparation is nevertheless cloudy yellow (homogeneous).
Answer
Try next water-free formula; Hopefully, they also manage for 5%.
fluphenamic acid 3.0 g Propylene glycol 12g Alcohol denatured with ether 82g Carbopol 980 3g
Preparation Mode
- Tarreer A receptacle of 150 to 200 ml with lid
- Place a magnetic rod on the bottom of the receptacle
- weigh: 12g propylene glycol and 82g antisept opl. and mix
- add slowly and stirring well 3g Carbopol 980
- mix for 10 min at low speed
- Remove the magnet rod and close the receptacle with the lid
- Place the receptacle in the freezer compartment of a refrigerator for 2 hours
- bring with degenerated alcohol weight taking into account the Tare
- Place the closed receptacle in the freezer compartment for one night
- let everything come to room temperature and add fluphenamic acid and mix to homogenous