To recipes helpdesk

Question

Posted on: March 6 2013

How can I process methoxsalone in (EC) Gelulen?

The Vrac product I received from Alpha-Pharma are exactly small cluttered needles, very soft in structure. When rubbing, they remain tangles together. How can I fix this?

Answer

I suspect that methoxsalone is soluble in alcohol. Dissolve the powder in the mortar in a small amount of alcohol and gradually add the required amount of lactose under good memgem. Let the alcohol evaporate under regular mixing of the mass. Allow the powder mixture to dry sufficiently long. Then complete this mass in capsules, which are then made gastric juice travel tent.

There is also the possibility to dissolve methoxsalan in oil and to fill this oil solution in capsules, a slightly more cumbersome way of working. But the resorption of Methoxsalone would be better in the presence of fats.