Question
Posted on: March 6 2013How to prepare best: Propylene glycol 3 G salicylic acid 3g LCD 4 G dermovate Lotion 30 ml Aqua Domus 30 ml isopropanol 30 ml
Answer
First of all, it should be said that, given the availability of Clobetasol propionate in "Vrac", the Dermovate lotion should be replaced by a loco preparation. Dermovate lotion contains Clobetasol propionate, Carbomeer, isopropyl alcohol, NaOH and water. For the sake of the addition of salicylic acid, carbomer should be replaced. We Choose 0, 5g hydroxypropylcellulose 400 (Klucel GF), which is compatible with large amounts of isopropanol.
of a 0.5% (M/V) clobetasolpropionate solution is 3 ml together with 3 G salicylic acid, 4 G LCD and 3 G propylene glycol mixed with 51 ml (21 + 30) isopropanol in which 0.5 g of Klucel GF is dissolved. With this solution, 30 ml of rosewater is added under stirring; Eventually, water is diluted to 97 ml.
of a 0.5% (M/V) clobetasolpropionate solution is 3 ml together with 3 G salicylic acid, 4 G LCD and 3 G propylene glycol mixed with 51 ml (21 + 30) isopropanol in which 0.5 g of Klucel GF is dissolved. With this solution, 30 ml of rosewater is added under stirring; Eventually, water is diluted to 97 ml.