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Question

Posted on: March 6 2013

Next to do not succeed: Ichtyol 250 mg papaverine HCl 80 mg Belladonna Dr Extr. 20 mg 20 to

The pouring out fails; All Ichtyol cools together and the mass is no longer homogeneous. Also not after adding 2.5 g Arlacel C.

Answer

I would prefer to use castor oil. A quantity of 5 g (for 20 suppositories) must be sufficient. Also add a 300 mg (per suppository) lactose to better distribute the Papaverine HCl and the Belladonna Dr Extr. Try with Witepsol W 45 as suppository Mass. I hope that there will be no major melting-point reduction.