Question
Posted on: March 6 2013What is the best solution to be able to make this ointment? Hydroquinte 2.5 g Triamcinolone Acetonide 50 mg Tretinoine 25 mg lactic acid 500 mg Glycerin 5 G Ascorbine acid 500
MG
Na. Edetaat 75 mg
White wax 3 G
Walschot 2.5 g
Cetiol V 15.5 g
Span 80 1 G
sorbitansesquioleate 4 G
Aqua Conservans AD 50 g < BR/> that is an oil-containing ointment (non-ionicum). To me & #039; breaks & #039; the ointment.
Na. Edetaat 75 mg
White wax 3 G
Walschot 2.5 g
Cetiol V 15.5 g
Span 80 1 G
sorbitansesquioleate 4 G
Aqua Conservans AD 50 g < BR/> that is an oil-containing ointment (non-ionicum). To me & #039; breaks & #039; the ointment.
Answer
This is a very complex composition. Why?
based on the choice of emulsifiers, a W/O cr è me is expected. Given the CR è me breaking, I would reinforce the emulsifier by replacing the white wax with cetyl alcohol in the composition.
the prescribed amount of water is required for dissolving the Hydroquina. For the triamcinolone acetonide a dilution 1:50 will have to be made if not this unresolved ingredient is not homogenous distributed over the CR è me.
based on the choice of emulsifiers, a W/O cr è me is expected. Given the CR è me breaking, I would reinforce the emulsifier by replacing the white wax with cetyl alcohol in the composition.
the prescribed amount of water is required for dissolving the Hydroquina. For the triamcinolone acetonide a dilution 1:50 will have to be made if not this unresolved ingredient is not homogenous distributed over the CR è me.