Question
Posted on: March 6 2013How do we best prepare the next tooth gel? Is This composition acceptable? Glycerin 10g after fluoride 0.1 g Ca carbonate heavy 5g chlorhexidine gluconate OPL 2.5 ml (20%) Hypromellose
hydroxypropylcellulose 2.5 g
mint Spiritus
water ad 100g < BR/>
Answer
- We must note that the activity of NaF is compromised by the presence of CaCO3, which can give rise to the formation of the insoluble CaF. Although some toothpaste & #039; s appear to have Cafluoride.
on the Internet can be read:
The most recognized toothpaste ingredient is probably the class of compounds known as fluorides. Stannous fluoride was the first to be used in toothpaste, because it could be used with the abrasive most common at the time, calcium phosphate. The calcium prevents sodium fluoride from being effective.
Later, sodium monofluorophosphate was used, as it also could be used with abrasives common at the time.
When hydrated Silica (AEROSIL) became the abrasive of choice, sodium fluoride could be used, and is the most widely used fluoride in toothpastes at this time.
Hydrated Silica is the transparent abrasive used in gel toothpastes, and in the clear parts of striped toothpaste. It has become common to use it in white opaque toothpastes as well, because of its compatibility with sodium fluoride.
- also a saturated solution of CaCO3 will have an alkaline pH (= 10), which will give rise to the precipitation of chlorhexidine. We can imagine that, under this form, the distribution of the antiseptic will not be as easy as possible. Here we can set CORSODYL toothpaste as an example.
- at the height of the preparation I see no major problems.